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Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome
G protein–coupled receptors (GPCRs), encoded by about 5% of human genes, comprise the largest family of integral membrane proteins and act as cell surface receptors responsible for the transduction of endogenous signal into a cellular response. Although tertiary structural information is crucial for...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364505/ https://www.ncbi.nlm.nih.gov/pubmed/16485037 http://dx.doi.org/10.1371/journal.pcbi.0020013 |