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Structure Modeling of All Identified G Protein–Coupled Receptors in the Human Genome

G protein–coupled receptors (GPCRs), encoded by about 5% of human genes, comprise the largest family of integral membrane proteins and act as cell surface receptors responsible for the transduction of endogenous signal into a cellular response. Although tertiary structural information is crucial for...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, DeVries, Mark E, Skolnick, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364505/
https://www.ncbi.nlm.nih.gov/pubmed/16485037
http://dx.doi.org/10.1371/journal.pcbi.0020013