Sequential activation of NKT cells and NK cells provides effective innate immunotherapy of cancer

The CD1d reactive glycolipid, α-galactosylceramide (α-GalCer), potently activates T cell receptor-α type I invariant NKT cells that secondarily stimulate the proliferation and activation of other leukocytes, including NK cells. Here we report a rational approach to improving the antitumor activity o...

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Detalles Bibliográficos
Autores principales: Smyth, Mark J., Wallace, Morgan E., Nutt, Stephen L., Yagita, Hideo, Godfrey, Dale I., Hayakawa, Yoshihiro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2005
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364507/
https://www.ncbi.nlm.nih.gov/pubmed/15967825
http://dx.doi.org/10.1084/jem.20042280

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1364507/
https://www.ncbi.nlm.nih.gov/pubmed/15967825
http://dx.doi.org/10.1084/jem.20042280

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