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Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium

BACKGROUND: Sliding DNA clamps are processivity factors that are required for efficient DNA replication. DNA polymerases maintain proximity to nucleic acid templates by interacting with sliding clamps that encircle DNA and thereby link the polymerase enzyme to the DNA substrate. Although the structu...

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Detalles Bibliográficos
Autores principales: Argiriadi, Maria A, Goedken, Eric R, Bruck, Irina, O'Donnell, Mike, Kuriyan, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368978/
https://www.ncbi.nlm.nih.gov/pubmed/16403212
http://dx.doi.org/10.1186/1472-6807-6-2