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A phase 1–2, prospective, double blind, randomized study of the safety and efficacy of Sulfasalazine for the treatment of progressing malignant gliomas: study protocol of [ISRCTN45828668]

BACKGROUND: The prognosis of patients suffering from WHO grade 3 and 4 astrocytic glioma remains poor despite surgery, radiation therapy and the use of current chemotherapy regimen. Indeed, the median survival of glioblastoma multiforme (WHO grade 4) patients is at best 14.6 month with only 26.5 per...

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Detalles Bibliográficos
Autores principales: Robe, Pierre A, Martin, Didier, Albert, Adelin, Deprez, Manuel, Chariot, Alain, Bours, Vincent
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368982/
https://www.ncbi.nlm.nih.gov/pubmed/16448552
http://dx.doi.org/10.1186/1471-2407-6-29