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Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

BACKGROUND: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regeneration. Following immune-mediated damage the beta-cell fate depends on several genes up- or down-regulated in parallel and/or...

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Detalles Bibliográficos
Autores principales: Magnusson, Nils E, Cardozo, Alessandra K, Kruhøffer, Mogens, Eizirik, Decio L, Ørntoft, Torben F, Jensen, Jens L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1368999/
https://www.ncbi.nlm.nih.gov/pubmed/16384535
http://dx.doi.org/10.1186/1471-2105-6-311