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Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys
BACKGROUND: Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels. To further investigate this question we examined the actions of isoflurane, TTX, extracel...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369004/ https://www.ncbi.nlm.nih.gov/pubmed/16409641 http://dx.doi.org/10.1186/1471-2202-7-5 |