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Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys

BACKGROUND: Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels. To further investigate this question we examined the actions of isoflurane, TTX, extracel...

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Detalles Bibliográficos
Autores principales: Winegar, Bruce D, MacIver, M Bruce
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369004/
https://www.ncbi.nlm.nih.gov/pubmed/16409641
http://dx.doi.org/10.1186/1471-2202-7-5