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High-throughput trapping of secretory pathway genes in mouse embryonic stem cells

High-throughput gene trapping is a random approach for inducing insertional mutations across the mouse genome. This approach uses gene trap vectors that simultaneously inactivate and report the expression of the trapped gene at the insertion site, and provide a DNA tag for the rapid identification o...

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Detalles Bibliográficos
Autores principales: De-Zolt, Silke, Schnütgen, Frank, Seisenberger, Claudia, Hansen, Jens, Hollatz, Melanie, Floss, Thomas, Ruiz, Patricia, Wurst, Wolfgang, von Melchner, Harald
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369290/
https://www.ncbi.nlm.nih.gov/pubmed/16478711
http://dx.doi.org/10.1093/nar/gnj026