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High-throughput trapping of secretory pathway genes in mouse embryonic stem cells
High-throughput gene trapping is a random approach for inducing insertional mutations across the mouse genome. This approach uses gene trap vectors that simultaneously inactivate and report the expression of the trapped gene at the insertion site, and provide a DNA tag for the rapid identification o...
Autores principales: | De-Zolt, Silke, Schnütgen, Frank, Seisenberger, Claudia, Hansen, Jens, Hollatz, Melanie, Floss, Thomas, Ruiz, Patricia, Wurst, Wolfgang, von Melchner, Harald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1369290/ https://www.ncbi.nlm.nih.gov/pubmed/16478711 http://dx.doi.org/10.1093/nar/gnj026 |
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