Intrathecal long-term gene expression by self-complementary adeno-associated virus type 1 suitable for chronic pain studies in rats

BACKGROUND: Intrathecal (IT) gene transfer is an attractive approach for targeting spinal mechanisms of nociception but the duration of gene expression achieved by reported methods is short (up to two weeks) impairing their utility in the chronic pain setting. The overall goal of this study was to d...

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Detalles Bibliográficos
Autores principales: Storek, Benjamin, Harder, Nina M, Banck, Michaela S, Wang, Cheng, McCarty, Douglas M, Janssen, William GM, Morrison, John H, Walsh, Christopher E, Beutler, Andreas S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373607/
https://www.ncbi.nlm.nih.gov/pubmed/16445862
http://dx.doi.org/10.1186/1744-8069-2-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373607/
https://www.ncbi.nlm.nih.gov/pubmed/16445862
http://dx.doi.org/10.1186/1744-8069-2-4

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