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A stochastic model of oncogene expression and the relevance of this model to cancer therapy

BACKGROUND: Ablation of an oncogene or of the activity of the protein it encodes can result in apoptosis and/or inhibit tumor cell proliferation. Therefore, if the oncogene or set of oncogenes contributing maximally to a tumor cell's survival can be identified, such oncogene(s) are the most app...

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Detalles Bibliográficos
Autor principal: Alfano, Francis D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373613/
https://www.ncbi.nlm.nih.gov/pubmed/16448558
http://dx.doi.org/10.1186/1742-4682-3-5