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Fas ligand expression in human and mouse cancer cell lines; a caveat on over-reliance on mRNA data

BACKGROUND: During carcinogenesis, tumors develop multiple mechanisms for evading the immune response, including upregulation of Fas ligand (FasL/CD95L) expression. Expression of FasL may help to maintain tumor cells in a state of immune privilege by inducing apoptosis of anti-tumor immune effector...

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Detalles Bibliográficos
Autores principales: Ryan, Aideen E, Lane, Sinead, Shanahan, Fergus, O'Connell, Joe, Houston, Aileen M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373622/
https://www.ncbi.nlm.nih.gov/pubmed/16457714
http://dx.doi.org/10.1186/1477-3163-5-5