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Fas ligand expression in human and mouse cancer cell lines; a caveat on over-reliance on mRNA data
BACKGROUND: During carcinogenesis, tumors develop multiple mechanisms for evading the immune response, including upregulation of Fas ligand (FasL/CD95L) expression. Expression of FasL may help to maintain tumor cells in a state of immune privilege by inducing apoptosis of anti-tumor immune effector...
Autores principales: | Ryan, Aideen E, Lane, Sinead, Shanahan, Fergus, O'Connell, Joe, Houston, Aileen M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373622/ https://www.ncbi.nlm.nih.gov/pubmed/16457714 http://dx.doi.org/10.1186/1477-3163-5-5 |
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