The GCC repeat length in the 5'UTR of MRP1 gene is polymorphic: a functional characterization of its relevance for cystic fibrosis

BACKGROUND: Among the members of the ATP binding cassette transporter superfamily, MRPs share the closest homology with the CFTR protein, which is defective in CF disease. MRP1 has been proposed as a potential modifier gene and/or as novel target for pharmacotherapy of CF to explain the clinical ben...

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Detalles Bibliográficos
Autores principales: Nicolis, Elena, Pasetto, Matteo, Cigana, Cristina, Pradal, Ugo, Assael, Baroukh M, Melotti, Paola
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373648/
https://www.ncbi.nlm.nih.gov/pubmed/16464259
http://dx.doi.org/10.1186/1471-2350-7-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373648/
https://www.ncbi.nlm.nih.gov/pubmed/16464259
http://dx.doi.org/10.1186/1471-2350-7-7

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