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D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

BACKGROUND: The family of c-Jun NH(2)-terminal kinases (JNK) plays important roles in embryonic development and in cellular responses to stress. Toxic metals and their compounds are potent activators of JNK in mammalian cells. The mechanism of mammalian JNK activation by cadmium and sodium arsenite...

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Detalles Bibliográficos
Autores principales: Ryabinina, Olga P, Subbian, Ezhilkani, Iordanov, Mihail S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373652/
https://www.ncbi.nlm.nih.gov/pubmed/16451733
http://dx.doi.org/10.1186/1471-2121-7-7