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Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I

Emergence of the bi-subunit topoisomerase I in the kinetoplastid family (Trypanosoma and Leishmania) has brought a new twist in topoisomerase research related to evolution, functional conservation and preferential sensitivities to the specific inhibitors of type IB topoisomerase family. In the prese...

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Detalles Bibliográficos
Autores principales: Das, Benu Brata, Sen, Nilkantha, Roy, Amit, Dasgupta, Somdeb Bose, Ganguly, Agneyo, Mohanta, Bikash Chandra, Dinda, Biswanath, Majumder, Hemanta K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373691/
https://www.ncbi.nlm.nih.gov/pubmed/16488884
http://dx.doi.org/10.1093/nar/gkj502