Cargando…
Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I
Emergence of the bi-subunit topoisomerase I in the kinetoplastid family (Trypanosoma and Leishmania) has brought a new twist in topoisomerase research related to evolution, functional conservation and preferential sensitivities to the specific inhibitors of type IB topoisomerase family. In the prese...
Autores principales: | Das, Benu Brata, Sen, Nilkantha, Roy, Amit, Dasgupta, Somdeb Bose, Ganguly, Agneyo, Mohanta, Bikash Chandra, Dinda, Biswanath, Majumder, Hemanta K. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373691/ https://www.ncbi.nlm.nih.gov/pubmed/16488884 http://dx.doi.org/10.1093/nar/gkj502 |
Ejemplares similares
-
‘LeishMan’ topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani
por: Ganguly, Agneyo, et al.
Publicado: (2006) -
ATP independent type IB topoisomerase of Leishmania donovani is stimulated by ATP: an insight into the functional mechanism
por: Sengupta, Souvik, et al.
Publicado: (2011) -
New Topoisomerase I mutations are associated with resistance to camptothecin
por: Gongora, Céline, et al.
Publicado: (2011) -
Poly(ADP-ribose) polymers regulate DNA topoisomerase I (Top1) nuclear dynamics and camptothecin sensitivity in living cells
por: Das, Subhendu K., et al.
Publicado: (2016) -
Targeting of Topoisomerase I for Prognoses and Therapeutics of Camptothecin-Resistant Ovarian Cancer
por: Lee, Yu-Chieh, et al.
Publicado: (2015)