Terminal DNA structure and ATP influence binding parameters of the DNA-dependent protein kinase at an early step prior to DNA synapsis

The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) regulates the non-homologous end-joining pathway of DNA double-strand break repair in mammalian cells. The ability of DNA-PKcs to sense and respond to different terminal DNA structures is postulated to be important for its regulatory func...

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Detalles Bibliográficos
Autores principales: Jovanovic, Marko, Dynan, William S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373693/
https://www.ncbi.nlm.nih.gov/pubmed/16488883
http://dx.doi.org/10.1093/nar/gkj504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373693/
https://www.ncbi.nlm.nih.gov/pubmed/16488883
http://dx.doi.org/10.1093/nar/gkj504

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