Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs

For many years, Taq polymerase has served as the stalwart enzyme in the PCR amplification of DNA. However, a major limitation of Taq is its inability to amplify damaged DNA, thereby restricting its usefulness in forensic applications. In contrast, Y-family DNA polymerases, such as Dpo4 from Sulfolob...

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Detalles Bibliográficos
Autores principales: McDonald, John P., Hall, Ashley, Gasparutto, Didier, Cadet, Jean, Ballantyne, Jack, Woodgate, Roger
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373694/
https://www.ncbi.nlm.nih.gov/pubmed/16488882
http://dx.doi.org/10.1093/nar/gkj512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1373694/
https://www.ncbi.nlm.nih.gov/pubmed/16488882
http://dx.doi.org/10.1093/nar/gkj512

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