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Haplotype analysis of the PPARγ Pro12Ala and C1431T variants reveals opposing associations with body weight
BACKGROUND: Variation at the PPARG locus may influence susceptibility to type 2 diabetes and related traits. The Pro12Ala polymorphism may modulate receptor activity and is associated with protection from type 2 diabetes. However, there have been inconsistent reports of its association with obesity....
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137581/ https://www.ncbi.nlm.nih.gov/pubmed/12429071 http://dx.doi.org/10.1186/1471-2156-3-21 |