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Haplotype analysis of the PPARγ Pro12Ala and C1431T variants reveals opposing associations with body weight

BACKGROUND: Variation at the PPARG locus may influence susceptibility to type 2 diabetes and related traits. The Pro12Ala polymorphism may modulate receptor activity and is associated with protection from type 2 diabetes. However, there have been inconsistent reports of its association with obesity....

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Detalles Bibliográficos
Autores principales:	Doney, Alex, Fischer, Bettina, Frew, David, Cumming, Alastair, Flavell, David M, World, Michael, Montgomery, Hugh E, Boyle, Douglas, Morris, Andrew, Palmer, Colin NA
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137581/ https://www.ncbi.nlm.nih.gov/pubmed/12429071 http://dx.doi.org/10.1186/1471-2156-3-21

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