Cargando…

Haplotype analysis of the PPARγ Pro12Ala and C1431T variants reveals opposing associations with body weight

BACKGROUND: Variation at the PPARG locus may influence susceptibility to type 2 diabetes and related traits. The Pro12Ala polymorphism may modulate receptor activity and is associated with protection from type 2 diabetes. However, there have been inconsistent reports of its association with obesity....

Descripción completa

Detalles Bibliográficos
Autores principales:	Doney, Alex, Fischer, Bettina, Frew, David, Cumming, Alastair, Flavell, David M, World, Michael, Montgomery, Hugh E, Boyle, Douglas, Morris, Andrew, Palmer, Colin NA
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2002
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC137581/ https://www.ncbi.nlm.nih.gov/pubmed/12429071 http://dx.doi.org/10.1186/1471-2156-3-21

Ejemplares similares

C1431T Variant of PPARγ Is Associated with Preeclampsia in Pregnant Women
por: Liu, Fulin, et al.
Publicado: (2021)

The C1431T polymorphism of peroxisome proliferator activated receptor γ (PPARγ) is associated with low risk of diabetes in a Pakistani cohort
por: Butt, Huma, et al.
Publicado: (2016)

PPARγ2(Pro12Ala) Polymorphism and Human Health
por: He, Weimin
Publicado: (2009)

Distribution and genotype frequency of the C1431T and pro12ala polymorphisms of the peroxisome proliferator activator receptor gamma gene in an Iranian population
por: Rooki, Hassan, et al.
Publicado: (2013)

Does Pro(12)Ala Polymorphism Enhance the Physiological Role of PPARγ2?
por: Pereira, A. C., et al.
Publicado: (2013)

Homozygosity for the Ala Allele of the PPARγ2 Pro12Ala Polymorphism Is Associated with Reduced Risk of Coronary Artery Disease
por: Galgani, Andrea, et al.
Publicado: (2010)

Effects Of PPARγ2 Pro12Ala Variant On Adipocyte Phenotype Dependent Of DHA
por: Wan, Renhui, et al.
Publicado: (2019)

Pro12Ala PPAR-γ2 and +294T/C PPAR-δ Polymorphisms and Association with Metabolic Traits in Teenagers from Northern Mexico
por: Carrillo-Venzor, Martín A., et al.
Publicado: (2020)

PPARγ Pro(12)Ala polymorphism and risk of acute coronary syndrome in a prospective study of Danes
por: Vogel, Ulla, et al.
Publicado: (2009)

PPARγ Pro12Ala and ACE ID polymorphisms are associated with BMI and fat distribution, but not metabolic syndrome
por: Passaro, Angela, et al.
Publicado: (2011)

Genotyping of peroxisome proliferator-activated receptor gamma (PPAR-γ) polymorphism (Pro12Ala) in Iranian population
por: Namvaran, Fatemeh, et al.
Publicado: (2011)

Association between PPAR-γ2 Pro12Ala genotype and insulin resistance is modified by circulating lipids in Mexican children
por: Stryjecki, Carolina, et al.
Publicado: (2016)

Relationships of dietary patterns with body composition in older adults differ by gender and PPAR-γ Pro12Ala genotype
por: Anderson, Amy L., et al.
Publicado: (2010)

The Pro12Ala Polymorphism of PPAR-γ Gene Is Associated with Sepsis Disease Severity and Outcome in Chinese Han Population
por: Ma, Guoda, et al.
Publicado: (2014)

Impact of the Pro12Ala polymorphism of the PPARγ2 gene on diabetes and obesity in a highly consanguineous population
por: Bener, Abdulbari, et al.
Publicado: (2015)

The PPARγ2 Pro12Ala variant is protective against progression of nephropathy in people with type 2 diabetes
por: Lapice, Emanuela, et al.
Publicado: (2015)

Molecular & biochemical analysis of Pro12Ala variant of PPAR-γ2 gene in type 2 diabetes mellitus
por: syed, Rabbani, et al.
Publicado: (2020)

PPARγ2 Pro12Ala Polymorphism is Associated in Children With Traits Related to Susceptibility to Type 2 Diabetes
por: Vales-Villamarín, Claudia, et al.
Publicado: (2021)

Haplotype Analysis of PPARγ Gene Polymorphisms and the Lipoprotein (a) Level
por: SHEN, Chao, et al.
Publicado: (2018)

Interaction Effects of the Leu162Val PPARα and Pro12Ala PPARγ2 Gene Variants with Renal Function in Metabolic Syndrome Population
por: Mohamed Youssef, Sarraj, et al.
Publicado: (2013)

Association between PRO12ALA polymorphism of the PPAR-γ2 gene and type 2 diabetes mellitus in Iranian patients
por: Motavallian, Azadeh, et al.
Publicado: (2013)

The Association of PPARγ Pro12Ala and C161T Polymorphisms with Polycystic Ovary Syndrome and Their Influence on Lipid and Lipoprotein Profiles
por: Rahimi, Zohreh, et al.
Publicado: (2018)

Breast-Feeding Modifies the Association of PPARγ2 Polymorphism Pro12Ala With Growth in Early Life: The Generation R Study
por: Mook-Kanamori, Dennis O., et al.
Publicado: (2009)

Changes in bone biological markers after treatment of Iranian diabetic patients with pioglitazone: No relation to polymorphism of PPAR-γ (Pro12Ala)
por: Namvaran, Fatemeh, et al.
Publicado: (2013)

Changes in bone biological markers after treatment of Iranian diabetic patients with pioglitazone: No relation to polymorphism of PPAR-γ (Pro12Ala)
por: Mottaghi, Peyman
Publicado: (2013)

The Pro12Ala polymorphism in the PPAR-γ2 gene is not associated to obesity and type 2 diabetes mellitus in a Cameroonian population
por: Mato, Edith Pascale M., et al.
Publicado: (2016)

Assessment of the Pro12Ala Polymorphism in the PPAR-γ2 Gene among Type 2 Diabetes Patients in a Nigerian Population
por: Engwa, Godwill Azeh, et al.
Publicado: (2018)

Pro12Ala Polymorphism on the PPAR(γ)2 Gene and Weight Loss After Aerobic Training: A Randomized Controlled Trial
por: Cardoso, Glêbia Alexa, et al.
Publicado: (2020)

Opposing roles for mammary epithelial-specific PPARγ signaling and activation during breast tumour progression
por: Apostoli, Anthony J, et al.
Publicado: (2015)

Discovery of PSR J0108-1431: the closest known neutron star?
por: Tauris, T M, et al.
Publicado: (1994)

The Association between the Pro12Ala Variant in the PPARγ2 Gene and Type 2 Diabetes Mellitus and Obesity in a Chinese Population
por: Wang, Xia, et al.
Publicado: (2013)

Association of PPARγ2 gene variant Pro12Ala polymorphism with hypertension and obesity in the aboriginal Qatari population known for being consanguineous
por: Bener, Abdulbari, et al.
Publicado: (2013)

The Pro12Ala polymorphism in the PPARγ2 gene is not associated with an increased risk of NAFLD in Iranian patients with type 2 diabetes mellitus
por: Saremi, Leila, et al.
Publicado: (2019)

Association of PPARγ2 (Pro12Ala) and Neuropeptide Y (Leu7Pro) Gene Polymorphisms with Obstructive Sleep Apnea in Obese Asian Indians
por: Bhushan, Bharat, et al.
Publicado: (2011)

IP receptor-dependent activation of PPARγ by stable prostacyclin analogues
por: Falcetti, Emilia, et al.
Publicado: (2007)

Interplay of Opposing Effects of the WNT/β-Catenin Pathway and PPARγ and Implications for SARS-CoV2 Treatment
por: Vallée, Alexandre, et al.
Publicado: (2021)

Impact of the PPAR-γ2 Pro12Ala Polymorphism and ACE Inhibitor Therapy on New-Onset Microalbuminuria in Type 2 Diabetes: Evidence From BENEDICT
por: De Cosmo, Salvatore, et al.
Publicado: (2009)

PPARγ2 Pro12Ala polymorphism was associated with favorable cardiometabolic risk profile in HIV/HCV coinfected patients: a cross-sectional study
por: García-Broncano, Pilar, et al.
Publicado: (2014)

1431. Comparison of Treatment Outcomes with Definitive Antibiotic Therapy and Empiric Antibiotic Therapy in Osteomyelitis
por: Holzum, Dorothy, et al.
Publicado: (2019)

ABX-1431 inhibits the development of endometrial adenocarcinoma and reverses progesterone resistance by targeting MGLL
por: Ma, Xiaohong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_6uvjh3auom13n68ad512bq26c5