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Making Ends Meet: Repairing Breaks in Bacterial DNA by Non-Homologous End-Joining

DNA double-strand breaks (DSBs) are one of the most dangerous forms of DNA lesion that can result in genomic instability and cell death. Therefore cells have developed elaborate DSB-repair pathways to maintain the integrity of genomic DNA. There are two major pathways for the repair of DSBs in eukar...

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Detalles Bibliográficos
Autores principales: Bowater, Richard, Doherty, Aidan J
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378119/
https://www.ncbi.nlm.nih.gov/pubmed/16518468
http://dx.doi.org/10.1371/journal.pgen.0020008