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Making Ends Meet: Repairing Breaks in Bacterial DNA by Non-Homologous End-Joining
DNA double-strand breaks (DSBs) are one of the most dangerous forms of DNA lesion that can result in genomic instability and cell death. Therefore cells have developed elaborate DSB-repair pathways to maintain the integrity of genomic DNA. There are two major pathways for the repair of DSBs in eukar...
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Formato: | Texto |
Lenguaje: | English |
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Public Library of Science
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1378119/ https://www.ncbi.nlm.nih.gov/pubmed/16518468 http://dx.doi.org/10.1371/journal.pgen.0020008 |