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Modulation of 5' splice site selection using tailed oligonucleotides carrying splicing signals

BACKGROUND: We previously described the use of tailed oligonucleotides as a means of reprogramming alternative pre-mRNA splicing in vitro and in vivo. The tailed oligonucleotides that were used interfere with splicing because they contain a portion complementary to sequences immediately upstream of...

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Detalles Bibliográficos
Autores principales: Gendron, Daniel, Carriero, Sandra, Garneau, Daniel, Villemaire, Jonathan, Klinck, Roscoe, Elela, Sherif Abou, Damha, Masad J, Chabot, Benoit
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1379639/
https://www.ncbi.nlm.nih.gov/pubmed/16412215
http://dx.doi.org/10.1186/1472-6750-6-5