Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins

BACKGROUND: The premature aging and cancer-prone Werner and Bloom syndromes are caused by defects in the RecQ helicase enzymes WRN and BLM, respectively. Recently, both WRN and BLM (as well as several other RecQ members) have been shown to possess a strand annealing activity in addition to the requi...

Descripción completa

Detalles Bibliográficos
Autores principales: Machwe, Amrita, Lozada, Enerlyn M, Xiao, Liren, Orren, David K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382243/
https://www.ncbi.nlm.nih.gov/pubmed/16412221
http://dx.doi.org/10.1186/1471-2199-7-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382243/
https://www.ncbi.nlm.nih.gov/pubmed/16412221
http://dx.doi.org/10.1186/1471-2199-7-1

Ejemplares similares