Sequential boundaries approach in clinical trials with unequal allocation ratios

BACKGROUND: In clinical trials, both unequal randomization design and sequential analyses have ethical and economic advantages. In the single-stage-design (SSD), however, if the sample size is not adjusted based on unequal randomization, the power of the trial will decrease, whereas with sequential...

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Detalles Bibliográficos
Autores principales: Jafari, Peyman, Ayatollahi, Seyyed Mohammad Taghi, Behboodian, Javad
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382245/
https://www.ncbi.nlm.nih.gov/pubmed/16412232
http://dx.doi.org/10.1186/1471-2288-6-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1382245/
https://www.ncbi.nlm.nih.gov/pubmed/16412232
http://dx.doi.org/10.1186/1471-2288-6-1

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