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Identification of Hepta- and Octo-Uridine stretches as sole signals for programmed +1 and −1 ribosomal frameshifting during translation of SARS-CoV ORF 3a variants

Programmed frameshifting is one of the translational recoding mechanisms that read the genetic code in alternative ways. This process is generally programmed by signals at defined locations in a specific mRNA. In this study, we report the identification of hepta- and octo-uridine stretches as sole s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoxing, Wong, Sek-Man, Liu, D. X.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383626/
https://www.ncbi.nlm.nih.gov/pubmed/16500894
http://dx.doi.org/10.1093/nar/gkl017