Killing the umpire: cooperative defects in mitotic checkpoint and BRCA2 genes on the road to transformation

Recent findings from mouse models of BRCA2 genetic lesions have provided intriguing insights and important questions concerning modes of tumor development in familial breast and ovarian cancers. Fibroblasts from mice homozygous for the BRCA2(Tr) allele grow poorly and display an array of chromosomal...

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Detalles Bibliográficos
Autor principal: McKeon, Frank
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 1999
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138502/
https://www.ncbi.nlm.nih.gov/pubmed/11250674
http://dx.doi.org/10.1186/bcr4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138502/
https://www.ncbi.nlm.nih.gov/pubmed/11250674
http://dx.doi.org/10.1186/bcr4

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