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Gamma radiation increases endonuclease-dependent L1 retrotransposition in a cultured cell assay
Long Interspersed Elements (LINE-1s, L1s) are the most active mobile elements in the human genome and account for a significant fraction of its mass. The propagation of L1 in the human genome requires disruption and repair of DNA at the site of integration. As Barbara McClintock first hypothesized,...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
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Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1385994/ https://www.ncbi.nlm.nih.gov/pubmed/16507671 http://dx.doi.org/10.1093/nar/gkj522 |