Cargando…
Role of BRCA gene dysfunction in breast and ovarian cancer predisposition
Tumor suppressor genes that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are mutated in the germline. The two major hereditary breast/ovarian cancer predisposition genes, BRCA1 and BRCA2, appear to participate in a common...
Autor principal: | |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138653/ https://www.ncbi.nlm.nih.gov/pubmed/11250724 http://dx.doi.org/10.1186/bcr76 |