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Examination of actin and microtubule dependent APC localisations in living mammalian cells

BACKGROUND: The trafficking of the adenomatous polyposis coli (APC) tumour suppressor protein in mammalian cells is a perennially controversial topic. Immunostaining evidence for an actin-associated APC localisation at intercellular junctions has been previously presented, though live imaging of mam...

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Detalles Bibliográficos
Autores principales: Langford, Kelly J, Askham, Jon M, Lee, Tracy, Adams, Matthew, Morrison, Ewan E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386658/
https://www.ncbi.nlm.nih.gov/pubmed/16423286
http://dx.doi.org/10.1186/1471-2121-7-3