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Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation

BACKGROUND: Laminin γ2 (Lamc2), one of the polypeptides in laminin-332 (laminin-5), is prominent in the basement membrane of alveolar walls and airways of developing and adult lung. Laminins are important for lung morphogenesis and based on its localization, a function for laminin γ2 in lung develop...

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Detalles Bibliográficos
Autores principales: Nguyen, Nguyet M, Pulkkinen, Leena, Schlueter, Jessica A, Meneguzzi, Guerrino, Uitto, Jouni, Senior, Robert M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386662/
https://www.ncbi.nlm.nih.gov/pubmed/16483354
http://dx.doi.org/10.1186/1465-9921-7-28