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Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity

BACKGROUND: Sumoylation has emerged as an important posttranslational regulatory mechanism for transcription factors and cofactors. Sumoylation of many transcription factors represses their transcriptional activities. The myocyte enhancer factor 2 (MEF2) family of transcription factors plays an impo...

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Detalles Bibliográficos
Autores principales: Kang, Jungseog, Gocke, Christian B, Yu, Hongtao
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386686/
https://www.ncbi.nlm.nih.gov/pubmed/16478538
http://dx.doi.org/10.1186/1471-2091-7-5