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Phosphorylation-facilitated sumoylation of MEF2C negatively regulates its transcriptional activity
BACKGROUND: Sumoylation has emerged as an important posttranslational regulatory mechanism for transcription factors and cofactors. Sumoylation of many transcription factors represses their transcriptional activities. The myocyte enhancer factor 2 (MEF2) family of transcription factors plays an impo...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386686/ https://www.ncbi.nlm.nih.gov/pubmed/16478538 http://dx.doi.org/10.1186/1471-2091-7-5 |