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Mutually Exclusive Expression of Virulence Genes by Malaria Parasites Is Regulated Independently of Antigen Production

The primary virulence determinant of Plasmodium falciparum malaria parasite–infected cells is a family of heterogeneous surface receptors collectively referred to as PfEMP1. These proteins are encoded by a large, polymorphic gene family called var. The family contains approximately 60 individual gen...

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Detalles Bibliográficos
Autores principales: Dzikowski, Ron, Frank, Matthias, Deitsch, Kirk
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1386720/
https://www.ncbi.nlm.nih.gov/pubmed/16518466
http://dx.doi.org/10.1371/journal.ppat.0020022