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Update on HER-2 as a target for cancer therapy: The ERBB2 promoter and its exploitation for cancer treatment
Overexpression of the ERBB2 proto-oncogene is associated with amplification of the gene in breast cancer but increased activity of the promoter also plays a significant role. Members of two transcription factor families (AP-2 and Ets) show increased binding to the promoter in over-expressing cells....
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2001
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138707/ https://www.ncbi.nlm.nih.gov/pubmed/11737892 http://dx.doi.org/10.1186/bcr329 |