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The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer

Cytokines, such as IL-6 and tumor necrosis factor (TNF)-α, have an important role in regulating estrogen synthesis in peripheral tissues, including normal and malignant breast tissues. The activities of the aromatase, estradiol 17β-hydroxysteroid dehydrogenase and estrone sulfatase are all increased...

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Detalles Bibliográficos
Autores principales: Purohit, Atul, Newman, Simon P, Reed, Michael J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138722/
https://www.ncbi.nlm.nih.gov/pubmed/11879566
http://dx.doi.org/10.1186/bcr425