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The role of cytokines in regulating estrogen synthesis: implications for the etiology of breast cancer
Cytokines, such as IL-6 and tumor necrosis factor (TNF)-α, have an important role in regulating estrogen synthesis in peripheral tissues, including normal and malignant breast tissues. The activities of the aromatase, estradiol 17β-hydroxysteroid dehydrogenase and estrone sulfatase are all increased...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138722/ https://www.ncbi.nlm.nih.gov/pubmed/11879566 http://dx.doi.org/10.1186/bcr425 |