Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer

The insulin-like growth factor (IGF) system exerts pleiotropic effects on mammalian cells. This review focuses on type I IGF receptor (IGF1R)-mediated signal transduction and its relevance in breast cancer. Upon activation by the IGFs, IGF1R, a transmembrane tyrosine kinase receptor, undergoes autop...

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Detalles Bibliográficos
Autores principales: Zhang, Xihong, Yee, Douglas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138771/
https://www.ncbi.nlm.nih.gov/pubmed/11250706
http://dx.doi.org/10.1186/bcr50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138771/
https://www.ncbi.nlm.nih.gov/pubmed/11250706
http://dx.doi.org/10.1186/bcr50

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