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Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer

The insulin-like growth factor (IGF) system exerts pleiotropic effects on mammalian cells. This review focuses on type I IGF receptor (IGF1R)-mediated signal transduction and its relevance in breast cancer. Upon activation by the IGFs, IGF1R, a transmembrane tyrosine kinase receptor, undergoes autop...

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Detalles Bibliográficos
Autores principales:	Zhang, Xihong, Yee, Douglas
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2000
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138771/ https://www.ncbi.nlm.nih.gov/pubmed/11250706 http://dx.doi.org/10.1186/bcr50

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