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A novel approach for rapid screening of mitochondrial D310 polymorphism

BACKGROUND: Mutations in the mitochondrial DNA (mtDNA) have been reported in a wide variety of human neoplasms. A polynucleotide tract extending from 303 to 315 nucleotide positions (D310) within the non-coding region of mtDNA has been identified as a mutational hotspot of primary tumors. This regio...

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Detalles Bibliográficos
Autores principales: Aral, Cenk, Kaya, Handan, Ataizi-Çelikel, Çiğdem, Akkiprik, Mustafa, Sönmez, Özgür, Güllüoğlu, Bahadır M, Özer, Ayşe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1388229/
https://www.ncbi.nlm.nih.gov/pubmed/16433919
http://dx.doi.org/10.1186/1471-2407-6-21