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Antigenomic delta ribozyme variants with mutations in the catalytic core obtained by the in vitro selection method
We have used the in vitro selection method to search for catalytically active variants of the antigenomic delta ribozyme with mutations in the regions that constitute the ribozyme active site: L3, J1/4 and J4/2. In the initial combinatorial library 16 nt positions were randomized and the library con...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1388270/ https://www.ncbi.nlm.nih.gov/pubmed/16513845 http://dx.doi.org/10.1093/nar/gkl018 |