Cargando…

From lymphocytes to sharks: V(D)J recombinase moves to the germline

The antigen-receptor genes of vertebrates are rearranged by a specialized somatic recombination mechanism in developing lymphocytes - and, unexpectedly, also in the germline of cartilaginous fishes. The recombination system that carries out these DNA rearrangements may thus be a significant evolutio...

Descripción completa

Detalles Bibliográficos
Autor principal: Roth, David B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC138851/
https://www.ncbi.nlm.nih.gov/pubmed/11178236