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State-dependent Block of CNG Channels by Dequalinium

Cyclic nucleotide–gated (CNG) ion channels are nonselective cation channels with a high permeability for Ca(2+). Not surprisingly, they are blocked by a number of Ca(2+) channel blockers including tetracaine, pimozide, and diltiazem. We studied the effects of dequalinium, an extracellular blocker of...

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Detalles Bibliográficos
Autores principales: Rosenbaum, Tamara, Gordon-Shaag, Ariela, Islas, León D., Cooper, Jeremy, Munari, Mika, Gordon, Sharona E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1389615/
https://www.ncbi.nlm.nih.gov/pubmed/14981138
http://dx.doi.org/10.1085/jgp.200308925