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Transforming growth factors-β are not good biomarkers of chemopreventive efficacy in a preclinical breast cancer model system

Using a carcinogen-initiated rat model of mammary tumorigenesis, we tested the hypothesis that transforming growth factor (TGF)-βs are useful biomarkers of chemopreventive efficacy in the breast. The chemopreventive agents tested were tamoxifen and the retinoids 9-cis-retinoic acid (9cRA) and N-(4-h...

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Detalles Bibliográficos
Autores principales: Zujewski, JoAnne, Vaughn-Cooke, Anika, Flanders, Kathleen C, Eckhaus, Michael A, Lubet, Ronald A, Wakefield, Lalage M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13902/
https://www.ncbi.nlm.nih.gov/pubmed/11250748