Cargando…

Integration of splicing, transport and translation to achieve mRNA quality control by the nonsense-mediated decay pathway

When pre-mRNAs are spliced, a multi-component complex is deposited onto them, close to the sites of intron removal. New findings suggest that these exon-exon junction complexes and the complexes that bind mRNA caps are key effectors of the fate of spliced mRNAs and may regulate whether mRNAs contain...

Descripción completa

Detalles Bibliográficos
Autores principales: Schell, Thomas, Kulozik, Andreas E, Hentze, Matthias W
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC139025/
https://www.ncbi.nlm.nih.gov/pubmed/11897029