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BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution
Germline mutations of the breast cancer associated gene 1 (BRCA1) predispose women to breast and ovarian cancers. BRCA1 is a large protein with multiple functional domains and interacts with numerous proteins that are involved in many important biological processes/pathways. Mounting evidence indica...
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| Formato: | Texto |
| Lenguaje: | English |
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Oxford University Press
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390683/ https://www.ncbi.nlm.nih.gov/pubmed/16522651 http://dx.doi.org/10.1093/nar/gkl010 |