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Homogeneous point mutation detection by quantum dot-mediated two-color fluorescence coincidence analysis
This report describes a new genotyping method capable of detecting low-abundant point mutations in a homogeneous, separation-free format. The method is based on integration of oligonucleotide ligation with a semiconductor quantum dot (QD)-mediated two-color fluorescence coincidence detection scheme....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390686/ https://www.ncbi.nlm.nih.gov/pubmed/16517937 http://dx.doi.org/10.1093/nar/gkl021 |