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Control of small inhibitory RNA levels and RNA interference by doxycycline induced activation of a minimal RNA polymerase III promoter

RNA interference (RNAi) mediated by expression of short hairpin RNAs (shRNAs) is a powerful tool for efficiently suppressing target genes. The approach allows studies of the function of individual genes and may also be applied to human therapy. However, in many instances regulation of RNAi by admini...

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Detalles Bibliográficos
Autores principales: Amar, Lahouari, Desclaux, Mathieu, Faucon-Biguet, Nicole, Mallet, Jacques, Vogel, Roland
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390691/
https://www.ncbi.nlm.nih.gov/pubmed/16522642
http://dx.doi.org/10.1093/nar/gkl034