Co-expression of anti-NFκB RNA aptamers and siRNAs leads to maximal suppression of NFκB activity in mammalian cells

The specific down-regulation of gene expression in cells is a powerful method for elucidating a gene's function. A common method for suppressing gene expression is the elimination of mRNA by RNAi or antisense. Alternatively, oligonucleotide-derived aptamers have been used as protein-directed ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Robert, Gilbert, Madaline, Thompson, Kristin M., Marsh, H. Nicholas, Epstein, David M., Pendergrast, P. Shannon
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390692/
https://www.ncbi.nlm.nih.gov/pubmed/16517938
http://dx.doi.org/10.1093/nar/gnj028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390692/
https://www.ncbi.nlm.nih.gov/pubmed/16517938
http://dx.doi.org/10.1093/nar/gnj028

Ejemplares similares