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Co-expression of anti-NFκB RNA aptamers and siRNAs leads to maximal suppression of NFκB activity in mammalian cells

The specific down-regulation of gene expression in cells is a powerful method for elucidating a gene's function. A common method for suppressing gene expression is the elimination of mRNA by RNAi or antisense. Alternatively, oligonucleotide-derived aptamers have been used as protein-directed ag...

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Detalles Bibliográficos
Autores principales:	Chan, Robert, Gilbert, Madaline, Thompson, Kristin M., Marsh, H. Nicholas, Epstein, David M., Pendergrast, P. Shannon
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2006
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1390692/ https://www.ncbi.nlm.nih.gov/pubmed/16517938 http://dx.doi.org/10.1093/nar/gnj028

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