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Estrogen receptor of primary breast cancers: evidence for intracellular proteolysis

INTRODUCTION: We previously reported that about two-thirds of [(125)I]oestradiol-labelled cytosolic ERs from breast cancer samples eluted as low-molecular-weight isoforms (≤ 37 kDa, size-exclusion fast pressure liquid chromatography [FPLC]). These isoforms failed to adsorb strongly to hydroxylapatit...

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Detalles Bibliográficos
Autores principales: Maaroufi, Younes, Lacroix, Marc, Lespagnard, Laurence, Journé, Fabrice, Larsimont, Denis, Leclercq, Guy
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13922/
https://www.ncbi.nlm.nih.gov/pubmed/11056692