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Dexamethasone protection from TNF-alpha-induced cell death in MCF-7 cells requires NF-kappaB and is independent from AKT

BACKGROUND: The biochemical bases for hormone dependence in breast cancer have been recognized as an important element in tumor resistance, proliferation and metastasis. On this respect, dexamethasone (Dex) dependent protection against TNF-alpha-mediated cell death in the MCF-7 cell line has been de...

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Detalles Bibliográficos
Autores principales: Machuca, Catalina, Mendoza-Milla, Criselda, Córdova, Emilio, Mejía, Salvador, Covarrubias, Luis, Ventura, José, Zentella, Alejandro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395311/
https://www.ncbi.nlm.nih.gov/pubmed/16504042
http://dx.doi.org/10.1186/1471-2121-7-9